N,N-Dimethylglycine HCI (DMG). Every effort has been made to ensure the accuracy of the Vetri FLEX information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert.
What is DMG?
Dimethylglycine is a highly unusual supplement, in that it is extremely popular despite the fact that all of its touted effects have largely been refuted by clinical and laboratory testing. It is most widely used as a performance enhancer by athletes, and in dogs and horses that are bred for racing purposes. Specifically, DMG is thought to be able to reduce lactic acid build up that might otherwise contribute to muscle fatigue. There is no immediately obvious reason why DMG should be able to achieve this, given its role in the body as a metabolite of betaine and a source of glycine. Reports of an ability of DMG to enhance athletic performance first appeared in the popular literature in the 1980's. Controlled studies involving treadmill horses, male athletes, and patients prone to lactic acid build up due to a cytochrome oxidase deficiency fail to support these earlier claims. Other common uses of DMG which have been refuted by clinical research include the treatment of autism and idiopathic epilepsy.
'.all of its touted effects have largely been refuted by clinical and laboratory testing.'
DMG is also touted as an immune stimulant, although it has no role in the body that could directly account for this effect. A double blind study in the early 1980's showed increased immune function (both humoral and cell-mediated) in humans following supplementation with DMG. Another study suggested this increased immune response could translate into a protective effect against cancer. A comprehensive study in 1992 failed to demonstrate any immune enhancing properties of DMG in cats.
What is the function of DMG?
DMG is a metabolite of betaine, which is used to help promote the production of methionine from homocysteine. Abnormal homocysteine levels are associated with autism and with coronary artery disease, but DMG does not stimulate reactions that reduce homocysteine, but is a by-product of them. DMG may also eventually be converted into two very vital compounds, phosphatidylserine and glutathione, but a direct effect has not been demonstrated. Indeed, in one study, DMG supplementation actually reduced glutathione levels.
'DMG does appear to function as an antioxidant, and has been shown to have a protective effect against gastric ulceration.'
DMG does appear to function as an antioxidant, and has been shown to have a protective effect against gastric ulceration.
Why recommend the administration of DMG to my pet?
Despite the lack of supportive research, DMG is used to enhance athletic performance in dogs and horses. It may also function as an antioxidant, and be of some benefit in reducing inflammation. DMG may also be recommended for the treatment of immune deficiency disorders, cancer, epilepsy and cognitive disorders, although research support for these uses is lacking.
How much experience is there with the use of DMG in pets?
DMG has been used for over 20 years in humans, racing dogs and horses. While not necessarily clinically effective, DMG is at least extremely well tolerated and very safe, which is not surprising given that it is a metabolite already present in the body. No toxicity has been reported to DMG supplementation. It is important to note that practitioners who use DMG are convinced of its efficacy, and report positive clinical outcomes, despite the lack of research support.
Where do I get DMG and do I need a prescription?
Pet owners are cautioned against buying supplements without knowledge of the manufacturer, as supplements are not highly regulated and some supplements may not contain the labelled amount of ingredients. Your veterinarian may have preferred supplements that he or she will recommend. A prescription is not needed for DMG.
This page contains information on Vetri DMG Liquid Formula for veterinary use.The information provided typically includes the following:
- Vetri DMG Liquid Formula Indications
- Warnings and cautions for Vetri DMG Liquid Formula
- Direction and dosage information for Vetri DMG Liquid Formula
Vetri DMG Liquid Formula
This treatment applies to the following species:Company: VetriScience
VETERINARIAN FORMULATED
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Supports Performance and Immune System Function
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IMMUNE HEALTH
CANINE, FELINE + AVIAN FORMULA
PRODUCT FACTS:
Active Ingredient Per ml:
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Each Drop Contains:
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N,N-Dimethylglycine (DMG) Dmg supplement to treat autism. | 6 mg |
Inactive Ingredients
citric acid, glycerin, malic acid, potassium sorbate, purified water, rosemary extract.
Cautions: Safe use in pregnant animals or animals intended for breeding has not been proven. If animal’s condition worsens or does not improve, stop product administration and consult your veterinarian.
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Recommended to help support proper immune response. Also helps maintain heart, skin, and brain health, and proper nerve functions.
Directions For Use
Dogs and Cats:
Up to 20 lbs: | 0.5 ml daily. |
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81 to 100 lbs: | 2.0 ml daily. |
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Birds:
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Warnings
For animal use only. Keep out of the reach of children and animals. In case of accidental overdose, contact a health professional immediately.Store in a cool, dry place.
MANUFACTURED IN THE U.S.A.*
*Manufactured in the USA with imported and domestic ingredients.
Distributed by VetriScience®Laboratories, A Division of FoodScience® Corporation, 929 Harvest Lane, Williston, VT 05495 USA
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WOMEN™ OWNED
Net Contents: | ||
1 fl oz (30 ml) | 0900590.030 | 1117A Skype download 8 17. |
3.85 fl oz (114 ml) | 0900590.120 | 0317A |
CPN: 6166053.6
VETRISCIENCE® LABORATORIESA Division of FoodScience® Corporation
929 HARVEST LANE, WILLISTON, VT, 05495
| Toll-Free: | 800-882-9993 |
| Fax: | 802-878-0549 |
| Website: | www.vetriscience.com |
| Email: | info@vetriscience.com |
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| Every effort has been made to ensure the accuracy of the Vetri DMG Liquid Formula information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert. |
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Copyright © 2020 Animalytix LLC. Updated: 2020-02-28